James Bond film: no girl and no villain
It is unusual for a project of this budget and scope to begin photography with 2 major cast elements unsettled.

Sony's "Casino Royale" kicked off its long-anticipated production in Prague on Friday. Although the globe-spanning shoot has locked down exotic locales and an intrigue-laden script, at least two things are still missing: a leading lady and a worthy opponent for Agent 007.
Source: hollywoodreporter.com