Security at The Plaza Hotel on Fifth Avenue called police just after 2 a.m. where they found Sheen, sources told The Post.
Tables and chairs had been thrown around the room and a chandelier was also damaged, sources said.
"The Two and a Half Men" star was accompanied to New York Hospital by his ex-wife Denise Richards, who was staying in a separate room.
Sheen, 45, told police he had been "out partying," sources said.
After he returned to his room with an unidentified woman, he noticed his wallet was missing, causing him to fly into a rage, sources said.
Sheen was in town with Denise Richards, 39, and their two daughters.
Fox News reported that Richards was in the city to promote her series "Blue Mountain State."
Sheen, Richards and their kids were spotted around the city this past weekend.
Source: NY Post